Fast hERG Liability Predictor
The Pred-hERG is a freely available web service for evaluation of cardiac toxicity via hERG inhibition. The predictions are made by predictive and extensively validated QSAR models. The Pred-hERG server employs many tools including flask, uWSGI, nginx, Python, and JavaScript. Towards more user-friendly interface, Pred-hERG provides an interactive web interface, including the JSME, a free molecule editor in JavaScript ,1 written on JavaScript and support the latest versions of all most popular browsers. Users will not need any Java or Flash plugins to use it in their browser. Pred-hERG is implemented on Ubuntu Server.
The new version of the web server has a simpler intuitive user interface. The user needs to paste the SMILES string of the structure in the appropriate area and hit ‘Predict’ button. After the completion of the job, the user will receive the outcome with the predicted probability maps in the page.